This study aimed to investigate the association between carotid artery calcification (CAC) on panoramic radiograph and intima-mediathickeness (IMT) measured on ultrasound. Panoramic radiographs which were taken from dental patients aged 50 years and olderwho visited for dental treatment were screened for the presence of CAC. The study group was composed of seven patients (fourmales and three females, average age 74.4±4.2 yrs) with CAC detected on panoramic radiographs, and the control group eleven patients(seven males and four females, average age 64.5±10.1 yrs) without CAC. All the patients underwent carotid ultrasonography to measurecarotid IMT. The IMT was compared between the groups by nonparametric analysis of covariance (ANCOVA). The range of IMT of the study group was 1.10~2.0 mm, while that of the control group 0.60~1.10 mm. The mean of IMT was1.50±0.34 mm in the study group and 0.85±0.14 mm in the control group, and there was statistically significant difference betweenthe two groups (p<.01). In conclusion, CAC detected on panoramic radiograph might have an association with atherosclerosis.