Research Hub

대학 자원

대학 인프라와 자원을 공유해 공동 연구와 기술 활용을 지원합니다.

논문 리스트

2019
Cytotoxic Constituents from the Roots of Asarum sieboldii in Human Breast Cancer Cells Cytotoxic Constituents from the Roots of Asarum sieboldii in Human Breast Cancer Cells
한국생약학회
강복윤
논문정보
Publisher
생약학회지
Issue Date
2019-03-29
Keywords
-
Citation
-
Source
-
Journal Title
-
Volume
25
Number
1
Start Page
72
End Page
75
DOI
ISSN
12263907
Abstract
Bioassay-guided fractionation of the roots of Asarum sieboldii led to the isolation of the six compounds methylkakuol (1), sesamin (2), asarinin (3), xanthoxylol (4), and (2E,4E,8Z,10E/Z)-N-(2-methylpropyl) dodeca-2,4,8,10-tetraenamide (5/6). Among the isolates, xanthoxylol (4) exhibited significant cytotoxicity against human breast cancer cells MCF-7 and MDA-MB-231 in vitro with IC50 values of 9.15 and 13.95 μM, respectively.
  • 전남대학교
  • KCI
  • 생약학회지

저자 정보

이름 소속
강복윤 약학부

목록보기