Candidal infection is recently reported to increase in certain predisposing condition, although isolated candidiasis from larynx is infrequently recognized and reported. Iisolated whitish lesions of vocal cord may be confused with precancerous lesions, squamous cell carcinoma, or verrucous carcinoma. A 62-year-old male visited our department for continuous hoarseness. Flexible laryngoscopy disclosed a whitish irregular exophytic mucosal lesion in right true vocal cord, which extended to anterior commissure and subglottis. Laryngeal microscopic surgery was done because of a concern regarding the possibility of glottic cancer. A pathologic biopsy revealed distorted and septated hypae and yeasts, scattered in moderate dysplasia. The patient was treated with itraconazole for 4 weeks, and followed up without any recurrence of candidiasis or dysplasia. (