Objectives: This study examined research trends by using text network analysis on studies concerning periodontal disease and systemic health published between 2015 and 2024. Methods: This study examines a corpus of 2,518 articles retrieved from the PubMed database, published between 2015 and 2024, which include the keywords [Systemic health AND periodontal disease] within their titles or abstracts. The selection criteria were not confined to any particular discipline, with data collection predicated on titles that encapsulate the primary focus of the research. The gathered data were analyzed using the Textom software (Textom 6.0, The IMC Co., Ltd., Korea) to clean and organize the information. From the top 100 words, a one-mode matrix was generated, followed by a centrality analysis. Results: In the last ten years, it has been established that studies on periodontal disease and overall health have been actively pursued, with new research areas steadily emerging. Conclusions: Research generating evidence for interventions aimed at managing periodontal disease should be further expanded, and investigations implementing these interventions within dental hygiene practice should be actively encouraged to enhance oral health outcomes.