This study examined whether mindfulness-based cognitive therapy (MBCT) effectively reduces anxiety and worry and enhances de-centering among university students. Twenty-four participants were randomly assigned to either the treatment group (n = 12) or the control group (n = 12). The treatment group received a four-session MBCT program. Results indicated that the treatment group showed statistically significant improvements in anxiety, worry, and metacognitive de-centering from pre- to post-test, whereas distanced de-centering did not demonstrate significant changes. These findings suggest that MBCT is effective in alleviating anxiety among university students and highlight de-centering as a core therapeutic mechanism within MBCT. The study contributes to the theoretical validation of MBCT and provides practical implications for interventions targeting anxiety in college populations.