This retrospective study was undertaken to compare the outcomes of staged bilateraltotal hip arthroplasty (THA) by the conventional approach with those of two-incisionminimally invasive (MIS-2) THA in terms of clinical and radiological results, complications,and patient preferences. Twenty-two patients aged 30 to 80 years underwentstaged bilateral THA. The conventional posterolateral approach was used on the firsthips treated and a modified MIS-2 approach on the second hips. The mean time betweenthe first and second procedures was 73.8 months, and the patients were followed upfor at least 12 months after both procedures. At the last follow-up visits, THA via theMIS-2 approach was found to provide significantly earlier partial-weight-bearing ambulation,better postoperative Harris hip scores, and better ability to sit cross-leggedand was found to be more preferred by patients than conventional THA. There wereno significant differences in the complication rates for the two approaches. The presentresults show that MIS-2 THA is as safe as the conventional posterolateral approachin experienced hands and presents no additional complication risks.