The purpose of this study was to examine the effects of family stress and family strengths on depression among married men and women. The subjects were 441 married men and women living in Gwangju and Seoul. The subjects completed a questionnaire and the data were analyzed using SPSS 18.0. The major findings were as follows; 1. The average scores of family stress and family strengths were higher than median. The general trends of depression showed lower than median. 2. Depressions were negatively related to family strengths, but were positively related to family stress. 3. Depressions were influenced by age, subjective health level, job, self-esteem, sex role attitudes, family stress and family strengths. In conclusion, to decrease married men and women'' depression, it is necessary to decrease family stress and increase family strengths.