Research Hub

대학 자원

대학 인프라와 자원을 공유해 공동 연구와 기술 활용을 지원합니다.

Loading...

논문 리스트

2010
유방암 수술 후 재발 소견으로 나타난 색소성 Paget 병 Pigmented Paget’s Disease: A Rare Clinical Manifestation of Recurred Breast Carcinoma
대한피부과학회
윤숙정, 이지범 외 2명
논문정보
Publisher
대한피부과학회지
Issue Date
2010-10-01
Keywords
-
Citation
-
Source
-
Journal Title
-
Volume
48
Number
10
Start Page
856
End Page
861
DOI
ISSN
04944739
Abstract
Pigmented mammary Paget’s disease is a rare variant of mammary Paget’s disease, and this mimics malignant melanoma both clinically and histopathologically. Two women aged 48 and 44 years old, respectively, presented with 2-cm pigmented patches and 1-cm pigmented erosive crusted papules without discharge or palpable masses, respectively. They had previously undergone breast-conserving surgery following the diagnosis of intraductal carcinoma of the breast. Physical examinations and imaging studies revealed no evidence of the recurrence of breast cancer. However, histopathological and immunohistochemical analyses demonstrated the presence of 1) Paget’s cells in the epidermis and these cells contained melanin within their cytoplasm and 2) numerous melanophages in the upper dermis. We diagnosed the two patients with pigmented Paget’s disease. Subsequent pathological analyses revealed recurrent intraductal carcinoma. We recommend that skin biopsies should be taken from patients presenting with pigmented lesions of the nipple, who have previously undergone breast-conserving treatment, to test the possibility of cancer recurrence. (Korean J Dermatol 2010;48(10):856∼861)

저자 정보

이름 소속
윤숙정 의학과
이지범 의학과