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2010
유방암 수술 후 재발 소견으로 나타난 색소성 Paget 병
Pigmented Paget’s Disease: A Rare Clinical Manifestation of Recurred Breast Carcinoma
대한피부과학회
윤숙정, 이지범 외 2명
논문정보
- Publisher
- 대한피부과학회지
- Issue Date
- 2010-10-01
- Keywords
- -
- Citation
- -
- Source
- -
- Journal Title
- -
- Volume
- 48
- Number
- 10
- Start Page
- 856
- End Page
- 861
- DOI
- ISSN
- 04944739
Abstract
Pigmented mammary Paget’s disease is a rare variant of mammary Paget’s disease, and this mimics malignant
melanoma both clinically and histopathologically. Two women aged 48 and 44 years old, respectively, presented
with 2-cm pigmented patches and 1-cm pigmented erosive crusted papules without discharge or palpable masses,
respectively. They had previously undergone breast-conserving surgery following the diagnosis of intraductal
carcinoma of the breast. Physical examinations and imaging studies revealed no evidence of the recurrence of breast
cancer. However, histopathological and immunohistochemical analyses demonstrated the presence of 1) Paget’s cells
in the epidermis and these cells contained melanin within their cytoplasm and 2) numerous melanophages in the
upper dermis. We diagnosed the two patients with pigmented Paget’s disease. Subsequent pathological analyses
revealed recurrent intraductal carcinoma. We recommend that skin biopsies should be taken from patients presenting
with pigmented lesions of the nipple, who have previously undergone breast-conserving treatment, to test the
possibility of cancer recurrence. (Korean J Dermatol 2010;48(10):856∼861)
- 전남대학교
- KCI
- 대한피부과학회지
저자 정보
| 이름 | 소속 |
|---|---|
| 윤숙정 | 의학과 |
| 이지범 | 의학과 |