Two-phase flow boiling heat transfer of R-410A in horizontal small tubes was reported in the present experimental study. The local heat transfer coefficients were obtained over a heat flux range of 5 to 40kW/㎡, a mass flux range of 170 to 600kg/㎡s, a saturation temperature range of 3 to 10℃, and quality up to 1.0. The test section was made of stainless steel tubes with inner diameters of 0.5 and 3.0 mm, and lengths of 330 and 3000mm, respectively. The test section was heated uniformly by applying a direct electric current to the tubes. The effects on heat transfer of mass flux, heat flux, inner tube diameter, and saturation temperature were presented. The experimental heat transfer coefficients are compared with six existing heat transfer coefficient correlations. A new boiling heat transfer coefficients correlation based on the superposition model for R-410A in small tubes was developed with mean deviation of 10.13%.