Iodinated contrast media (CM) can cause immediate and late reactions. We treated a patient with a recurrent generalized maculopapular rash and a fever that occurred within two days of exposure to iodinated CM, iopromide (Ultravist？), for chest computed tomography. We performed skin testing including prick tests, intradermal tests, and patch tests. Our findings indicated a late skin reaction to Ultravist?in addition to cross-reactions to other iodinated CM such as ioversol (Optiray？), iohexol (Iobrix？), and iobitridol (Xenetix？). In this study, we report the case of a patient diagnosed with a late adverse reaction to Ultravist?in addition to cross-reactions to other iodinated CM.