The purpose of this study was to test the mediating effect of ego resilience in relation between physical self-concept and interpersonal competence. The participants were 305 sport-majored college students. All the students administered three instruments, Physical Self-Description Questionnaire, Ego-Resiliency Scale, Interpersonal Competence Questionnaire. The results of this study were as follows: First, physical self-concept was significantly related to interpersonal competence. Second, physical self-concept was significantly related to ego resilience. Third, ego resilience was significantly related to interpersonal relationship. Forth, it was proved that ego resilience exerted as mediating variable between phsycial self-concept and interpersonal relationship. The implications of this study were investigated variables regarding interpersonal competence for sport-majored college students. Based on the finding results, discussion and implication for further research were suggested.