A supply chain has always exposed to a risk of destruction and disruption. This paper, therefore, analyzes that arisk of destruction and disruption affects to a supply chain and the simulation model of a supply chain is modeled andexpressed by agent-based modeling and System Dynamics. AnyLogic is used as a modeling tool because it flexiblyassociates an agent model and System Dynamics. This study makes 3 test cases which reflect the effect ofdestruction and disruption to evaluate the risk of a supply chain. Finally this paper analyzes the results and proposesan alternative.