Purpose: This study examined the clinical practice-related stress, academic burnout, stress coping styles, and sleep quality of nursing students, as well as the factors affecting sleep quality. Method: Data were collected from 240 nursing students in their third and fourth years who had completed their clinical practice at two universities from April 16 to April 29, 2024. General characteristics, sleep quality, stress associated with clinical practice, academic burnout and stress cop- ing style were assessed using a structured questionnaire. The data were analyzed using the SPSS/WIN 27.0 program with descriptive statistics, independent t-test, one-way ANOVA, Pearson's correlation coefficients, and multiple regression. Result: Positive correlations were observed between sleep quality and clinical practice related stress and academic burn- out, while the stress coping style was negatively correlated with sleep quality. The key factors influencing sleep quality included average sleep duration, mental health status, subjective health status, satisfaction with clinical practice, and aca- demic burnout. The explanatory power of these variables was 43.8% (F=15.32, p<.001). Conclusion: It is necessary to develop and apply a multifaceted program that can improve the sleep quality of nursing students with clinical practice experience.